| Product Name |
Recombinant Human Molybdenum Cofactor Synthesis 2 (MOCS2) Protein |
| Product Overview |
This recombinant human Molybdenum Cofactor Synthesis 2 (MOCS2) protein includes amino acids 1-188aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O96007 |
| Recommended Name |
Molybdopterin synthase catalytic subunit |
| Gene Name |
MOCS2 |
| Synonyms |
molybdenum cofactor synthesis 2 , MCBPE, MOCO1, MOCS2A, MOCS2B, MPTS. |
| Species |
Human |
| Predicted Molecular Mass |
25 kDa |
| Expression System |
E.coli |
| Expression Range |
1-188aa |
| Tag |
N-6His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. |
| Subcellular Location |
Cytoplasm, cytosol. |
| Protein Family |
MoaE family, MOCS2B subfamily |
| Associated Diseases |
Molybdenum cofactor deficiency, complementation group B (MOCODB) |
| Tissue Specificity |
Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes. |
