| Product Name |
Recombinant Human MGAT2 Protein |
| Product Overview |
This recombinant human MGAT2 protein includes amino acids 30-447aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerolprior to lyophilization. |
| Target Uniprot Id |
Q10469 |
| Recommended Name |
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
| Gene Name |
MGAT2 |
| Synonyms |
Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase , CDGS2, GLCNACTII, GNT-II, GNT2 |
| Species |
Human |
| Predicted Molecular Mass |
50 kDa (439aa) |
| Expression System |
E.coli |
| Expression Range |
30-447aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Plays an essential role in protein N-glycosylation. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free terminal mannose moiety in the core structure of the nascent N-linked glycan chain, giving rise to the second branch in complex glycans. |
| Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein. |
| Protein Family |
Glycosyltransferase 16 (GT16) protein family |
| Associated Diseases |
Congenital disorder of glycosylation 2A (CDG2A) |
