| Product Name |
Recombinant Human LTA Protein |
| Product Overview |
This recombinant human LTA protein includes amino acids 35-205aa of the target gene is expressed in Baculovirus-Insect Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P01374 |
| Recommended Name |
Lymphotoxin-alpha |
| Gene Name |
LTA |
| Synonyms |
Lymphotoxin alpha, LTA, LT, TNFB, TNFSF1, TNLG1E, LTalpha, DIF, LT, LT alpha, LT-alpha, Lta, Lymphot |
| Species |
Human |
| Predicted Molecular Mass |
19.7 kDa |
| Expression System |
Insect Cell |
| Expression Range |
35-205aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer, Signal Transduction |
| Target Function |
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. |
| Subcellular Location |
Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated. |
| Protein Family |
Tumor necrosis factor family |
| Associated Diseases |
Psoriatic arthritis (PSORAS) |
