Product Name |
Recombinant Human Left/Right Determination Factor 2 (LEFTY2) Protein |
Product Overview |
This recombinant human Left/Right Determination Factor 2 (LEFTY2) protein includes amino acids 245-356aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
Target Uniprot Id |
O00292 |
Recommended Name |
Left-right determination factor 2 |
Gene Name |
LEFTY2 |
Synonyms |
TGFB4; EBAF; LEFTA; LEFTYA; Endometrial Bleeding Associated Factor; Left-right determination factor |
Species |
Human |
Predicted Molecular Mass |
17 kDa |
Expression System |
E.coli |
Expression Range |
245-356aa |
Tag |
N-6His |
Purity |
>90% |
Formulation |
Lyophilized |
Buffer |
PBS |
Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
Research Area |
Cancer |
Target Function |
Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. |
Subcellular Location |
Secreted. |
Protein Family |
TGF-beta family |
Associated Diseases |
Left-right axis malformations (LRAM) |
Tissue Specificity |
Mesenchymal cells of the endometrial stroma. |