| Product Name |
Recombinant Human Laminin Beta 2 (LAMb2) Protein |
| Product Overview |
This recombinant human Laminin Beta 2 (LAMb2) protein includes amino acids 38-350aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P55268 |
| Recommended Name |
Laminin subunit beta-2 |
| Gene Name |
LAMB2 |
| Synonyms |
LAM-B2; LAMS; Laminin S; Laminin B1s chain; S-laminin subunit beta |
| Species |
Human |
| Predicted Molecular Mass |
66 kDa |
| Expression System |
E.coli |
| Expression Range |
38-350aa |
| Tag |
N-6His+GST |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cell Adhesion |
| Target Function |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane. Note=S-laminin is concentrated in the synaptic cleft of the neuromuscular junction. |
| Associated Diseases |
Pierson syndrome (PIERSS); Nephrotic syndrome 5 with or without ocular abnormalities (NPHS5) |
