| Product Name |
Recombinant Human KRT16 Protein |
| Product Overview |
This recombinant human KRT16 protein includes amino acids 1-473aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P08779 |
| Recommended Name |
Keratin, type I cytoskeletal 16 |
| Gene Name |
KRT16 |
| Synonyms |
Keratin, type I cytoskeletal 16, CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK |
| Species |
Human |
| Predicted Molecular Mass |
53.7 kDa |
| Expression System |
E.coli |
| Expression Range |
1-473aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. |
| Protein Family |
Intermediate filament family |
| Associated Diseases |
Pachyonychia congenita 1 (PC1); Keratoderma, palmoplantar, non-epidermolytic, focal 1 (FNEPPK1) |
| Tissue Specificity |
Expressed in the corneal epithelium (at protein level). |
