| Product Name |
Recombinant Human Hyaluronidase-1/HYAL1 Protein |
| Product Overview |
This recombinant human Hyaluronidase-1/HYAL1 protein includes amino acids 22-435aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q12794 |
| Recommended Name |
Hyaluronidase-1 |
| Gene Name |
HYAL1 |
| Synonyms |
Hyaluronidase-1; Hyal-1; Hyaluronoglucosaminidase-1; Lung Carcinoma Protein 1; LuCa-1; HYAL1; LUCA1 |
| Species |
Human |
| Predicted Molecular Mass |
47.2 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
22-435aa |
| Tag |
C-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. |
| Subcellular Location |
Secreted. Lysosome. |
| Protein Family |
Glycosyl hydrolase 56 family |
| Associated Diseases |
Mucopolysaccharidosis 9 (MPS9) |
| Tissue Specificity |
Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node sp |
