| Product Name |
Recombinant Human GDNF Family Receptor α-1/GFRA1 Protein |
| Product Overview |
This recombinant human GDNF Family Receptor α-1/GFRA1 protein includes amino acids 25-429aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P56159 |
| Recommended Name |
GDNF family receptor alpha-1 |
| Gene Name |
GFRA1 |
| Synonyms |
GDNF Family Receptor Alpha-1; GDNF Receptor Alpha-1; GDNFR-Alpha-1; GFR-Alpha-1; RET Ligand 1; TGF-B |
| Species |
Human |
| Predicted Molecular Mass |
72.3 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
25-429aa |
| Tag |
C-Fc |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Neuroscience |
| Target Function |
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. |
| Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus, trans-Golgi network. Endosome. Endosome, multivesicular body. |
| Protein Family |
GDNFR family |
