| Product Name |
Recombinant Human Gelsolin (GSN) Protein |
| Product Overview |
This recombinant human Gelsolin (GSN) protein includes amino acids 28-782aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P06396 |
| Recommended Name |
Gelsolin |
| Gene Name |
GSN |
| Synonyms |
GS; AGEL; ADF; Brevin |
| Species |
Human |
| Predicted Molecular Mass |
87 kDa |
| Expression System |
E.coli |
| Expression Range |
28-782aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. |
| Subcellular Location |
[Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 1]: Secreted. |
| Protein Family |
Villin/gelsolin family |
| Associated Diseases |
Amyloidosis 5 (AMYL5) |
| Tissue Specificity |
Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells. |
