| Product Name |
Recombinant Human Bone Morphogenetic 9 (BMP9/GDF2) Protein |
| Product Overview |
This recombinant human Bone Morphogenetic 9 (BMP9/GDF2) protein includes amino acids 320-429 of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitolprior to lyophilization. |
| Target Uniprot Id |
Q9UK05 |
| Recommended Name |
Growth/differentiation factor 2 |
| Gene Name |
GDF2 |
| Synonyms |
GDF2; Growth Differentiation Factor 2 |
| Species |
Human |
| Predicted Molecular Mass |
15kDa |
| Expression System |
E.coli |
| Expression Range |
320-429 |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cell Biology |
| Target Function |
Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. |
| Subcellular Location |
Secreted. |
| Protein Family |
TGF-beta family |
| Associated Diseases |
Telangiectasia, hereditary hemorrhagic, 5 (HHT5) |
| Tissue Specificity |
Detected in blood plasma (at protein level). |
