| Product Name |
Recombinant Human Fibronectin Type III Domain Containing 5 (FNDC5) Protein |
| Product Overview |
This recombinant human Fibronectin Type III Domain Containing 5 (FNDC5) protein includes amino acids 32-143aa of the target gene is expressed in 293F cell.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
Q8NAU1 |
| Recommended Name |
Fibronectin type III domain-containing protein 5 |
| Gene Name |
FNDC5 |
| Synonyms |
FRCP2; Irisin; Fibronectin type III repeat-containing protein 2 |
| Species |
Human |
| Predicted Molecular Mass |
27 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
32-143aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cell Biology |
| Target Function |
Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. |
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein.; [Irisin]: Secreted. |
| Tissue Specificity |
Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen. |
