| Product Name |
Recombinant Human Family With Sequence Similarity 20, Member A (FAM20A) Protein |
| Product Overview |
This recombinant human Family With Sequence Similarity 20, Member A (FAM20A) protein includes amino acids 368-523 of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitolprior to lyophilization. |
| Target Uniprot Id |
Q96MK3 |
| Recommended Name |
Pseudokinase FAM20A |
| Gene Name |
FAM20A |
| Species |
Human |
| Predicted Molecular Mass |
24kDa |
| Expression System |
E.coli |
| Expression Range |
368-523 |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cell Biology |
| Target Function |
Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
| Subcellular Location |
Secreted. Golgi apparatus. Endoplasmic reticulum. |
| Protein Family |
FAM20 family |
| Associated Diseases |
Amelogenesis imperfecta 1G (AI1G) |
| Tissue Specificity |
Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
