| Product Name |
Recombinant Human Coagulation Factor IX / FIX / F9 Protein |
| Product Overview |
This recombinant human Coagulation Factor IX / FIX / F9 protein includes amino acids 1-461aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P00740 |
| Recommended Name |
Coagulation factor IX |
| Gene Name |
F9 |
| Synonyms |
Coagulation factor 9;Coagulation factor IX;FIX;HEMB;P19;PTC;THPH8 |
| Species |
Human |
| Predicted Molecular Mass |
50 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
1-461aa |
| Tag |
C-His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular |
| Target Function |
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. |
| Subcellular Location |
Secreted. |
| Protein Family |
Peptidase S1 family |
| Associated Diseases |
Hemophilia B (HEMB); Thrombophilia, X-linked, due to factor IX defect (THPH8) |
| Tissue Specificity |
Detected in blood plasma (at protein level). Synthesized primarily in the liver and secreted in plasma. |
