| Product Name |
Recombinant Human Esophageal Cancer Related Gene 4 (ECRG4) Protein |
| Product Overview |
This recombinant human Esophageal Cancer Related Gene 4 (ECRG4) protein includes amino acids 32-148aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
Q9H1Z8 |
| Recommended Name |
Augurin |
| Gene Name |
ECRG4 |
| Synonyms |
C2orf40; Augurin |
| Species |
Human |
| Predicted Molecular Mass |
18 kDa |
| Expression System |
E.coli |
| Expression Range |
32-148aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system. ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation. |
| Subcellular Location |
Secreted. Cytoplasm. Apical cell membrane. |
| Protein Family |
Augurin family |
| Tissue Specificity |
Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level). |
