| Product Name |
Recombinant Human Dopamine Receptor D2 (DRD2) Protein |
| Product Overview |
This recombinant human Dopamine Receptor D2 (DRD2) protein includes amino acids 200-384aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P14416 |
| Recommended Name |
D(2) dopamine receptor |
| Gene Name |
DRD2 |
| Synonyms |
DR-D2; D2DR; D2R |
| Species |
Human |
| Predicted Molecular Mass |
26 kDa |
| Expression System |
E.coli |
| Expression Range |
200-384aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
G-Protein Coupled Receptor, Receptor, Transducer |
| Target Function |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. |
| Protein Family |
G-protein coupled receptor 1 family |
| Tissue Specificity |
[Isoform 1]: Expressed in the anterior pituitary gland.; [Isoform 2]: Expressed in the anterior pituitary gland. |
