| Product Name |
Recombinant Human DNAJC19 Protein |
| Product Overview |
This recombinant human DNAJC19 protein includes amino acids 19-116aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q96DA6 |
| Recommended Name |
Mitochondrial import inner membrane translocase subunit TIM14 |
| Gene Name |
DNAJC19 |
| Synonyms |
Mitochondrial import inner membrane translocase subunit TIM14, Pam18, TIM14, TIMM14. |
| Species |
Human |
| Predicted Molecular Mass |
15.1 kDa |
| Expression System |
E.coli |
| Expression Range |
19-116aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Mitochondrial co-chaperone which forms a complex with prohibitins to regulate cardiolipin remodeling. May be a component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity. |
| Subcellular Location |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
| Protein Family |
TIM14 family |
| Associated Diseases |
3-methylglutaconic aciduria 5 (MGA5) |
| Tissue Specificity |
Ubiquitously expressed. |
