| Description |
Recombinant Human CXCL16 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asn30-Thr205. |
| Purity |
> 95% as determined by Tris-Bis PAGE |
| Accession |
Q9H2A7 |
| Target Symbol |
CXCL16 |
| Synonyms |
SR-PSOX; CXCLG16; SRPSOX; CXCL16; SCYB16 |
| Species |
Human |
| Expression System |
HEK293 |
| Tag |
C-hFc |
| Expression Range |
Asn30-Thr205 |
| Mol. Weight |
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result. |
| Form |
Lyophilized |
| Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping |
Shipped at ambient temperature. |
| Gene Background |
CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall cells, leukocytes and platelets express and/or release CXCL16 under the regulation of inflammatory mediators. CXCL16 expression is increased in experimental and human nephropathies. Targeting CXCL16 protected from experimental glomerular injury or interstitial fibrosis. |
