| Product Name |
Recombinant Human B-Lymphocyte Chemoattractant (BLC/CXCL13) Protein |
| Product Overview |
This recombinant human B-Lymphocyte Chemoattractant (BLC/CXCL13) protein includes amino acids 23-94aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O43927 |
| Recommended Name |
C-X-C motif chemokine 13 |
| Gene Name |
CXCL13 |
| Synonyms |
C-X-C motif chemokine 13 precursor, Chemokine (C-X-C motif) ligand 13, ANGIE, ANGIE2, BCA-1, BCA1, B |
| Species |
Human |
| Predicted Molecular Mass |
17 kDa |
| Expression System |
E.coli |
| Expression Range |
23-94aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5. |
| Subcellular Location |
Secreted. |
| Protein Family |
Intercrine alpha (chemokine CxC) family |
| Tissue Specificity |
Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen. |