| Product Name |
Recombinant Human Collagen Type XI Alpha 1 (COL11a1) Protein |
| Product Overview |
This recombinant human Collagen Type XI Alpha 1 (COL11a1) protein includes amino acids 1564-1806aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P12107 |
| Recommended Name |
Collagen alpha-1(XI) chain |
| Gene Name |
COL11A1 |
| Synonyms |
COL11-A1; CO11A1; COLL6; STL2; Collagen Alpha-1(XI)chain |
| Species |
Human |
| Predicted Molecular Mass |
33 kDa |
| Expression System |
E.coli |
| Expression Range |
1564-1806aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Others |
| Target Function |
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. |
| Subcellular Location |
Secreted, extracellular space, extracellular matrix. |
| Protein Family |
Fibrillar collagen family |
| Associated Diseases |
Stickler syndrome 2 (STL2); Marshall syndrome (MRSHS); Fibrochondrogenesis 1 (FBCG1) |
| Tissue Specificity |
Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon. |
