| Product Name |
Recombinant Human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) Protein |
| Product Overview |
This recombinant human Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 (CEACAM8) protein includes amino acids 75-220aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P31997 |
| Recommended Name |
Cell adhesion molecule CEACAM8 |
| Gene Name |
CEACAM8 |
| Synonyms |
CD67; CD66-B; CD66b; CGM6; NCA95; Carcinoembryonic antigen CGM6; Non-specific cross-reacting antigen |
| Species |
Human |
| Predicted Molecular Mass |
26 kDa |
| Expression System |
E.coli |
| Expression Range |
75-220aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor. Cell surface. |
| Protein Family |
Immunoglobulin superfamily, CEA family |
| Tissue Specificity |
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. |
