| Product Name |
Recombinant Human CEACAM8/CD66b Protein |
| Product Overview |
This recombinant human CEACAM8/CD66b protein includes amino acids 35-141aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P31997 |
| Recommended Name |
Cell adhesion molecule CEACAM8 |
| Gene Name |
CEACAM8 |
| Synonyms |
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8; CD67 Antigen; Carcinoembryonic Antigen CG |
| Species |
Human |
| Predicted Molecular Mass |
13 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
35-141aa |
| Tag |
C-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor. Cell surface. |
| Protein Family |
Immunoglobulin superfamily, CEA family |
| Tissue Specificity |
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow. |
