Product Name |
Recombinant Human Cysteine Dioxygenase Type 1/CDO1 Protein |
Product Overview |
This recombinant human Cysteine Dioxygenase Type 1/CDO1 protein includes amino acids 1-200aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
Target Uniprot Id |
Q16878 |
Recommended Name |
Cysteine dioxygenase type 1 |
Gene Name |
CDO1 |
Synonyms |
Cysteine Dioxygenase Type 1; Cysteine Dioxygenase Type I; CDO; CDO-I; CDO1 |
Species |
Human |
Predicted Molecular Mass |
25.1 kDa |
Expression System |
E.coli |
Expression Range |
1-200aa |
Tag |
N-6His |
Purity |
>85% |
Formulation |
Lyophilized |
Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
Research Area |
Signal Transduction |
Target Function |
Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. |
Protein Family |
Cysteine dioxygenase family |
Tissue Specificity |
Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells. |