| Product Name |
Recombinant Human CD27 Ligand/TNFSF7/CD70 Protein |
| Product Overview |
This recombinant human CD27 Ligand/TNFSF7/CD70 protein includes amino acids 45-193aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P32970 |
| Recommended Name |
CD70 antigen |
| Gene Name |
CD70 |
| Synonyms |
CD70 antigen;CD70;CD27 ligand;Tumor necrosis factor ligand superfamily member 7;CD27LG; TNFSF7;CD27L |
| Species |
Human |
| Predicted Molecular Mass |
43.6 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
45-193aa |
| Tag |
C-Fc |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunity, Cancer |
| Target Function |
Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. |
| Subcellular Location |
Membrane; Single-pass type II membrane protein. |
| Protein Family |
Tumor necrosis factor family |
