| Product Name |
Recombinant Human C-C chemokine receptor type 1(CCR1) Protein |
| Product Overview |
This recombinant human C-C chemokine receptor type 1(CCR1) protein includes amino acids 1-34aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P32246 |
| Recommended Name |
C-C chemokine receptor type 1 |
| Gene Name |
CCR1 |
| Synonyms |
type 1 CCR1, CMKBR1, CMKR1, SCYAR1 |
| Species |
Human |
| Predicted Molecular Mass |
30 kDa |
| Expression System |
E.coli |
| Expression Range |
1-34aa |
| Tag |
N-His-GST |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. |
| Protein Family |
G-protein coupled receptor 1 family |
| Tissue Specificity |
Widely expressed in different hematopoietic cells. |
