| Product Name |
Recombinant Human CA12 Protein |
| Product Overview |
This recombinant human CA12 protein includes amino acids 25-301aa of the target gene is expressed in Insect cell.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O43570 |
| Recommended Name |
Carbonic anhydrase 12 |
| Gene Name |
CA12 |
| Synonyms |
Carbonic anhydrase 12 isoform 1, CAXII, HsT18816 |
| Species |
Human |
| Predicted Molecular Mass |
31.94 kDa |
| Expression System |
Insect Cell |
| Expression Range |
25-301aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Reversible hydration of carbon dioxide. |
| Subcellular Location |
Membrane; Single-pass type I membrane protein. Cell membrane. |
| Protein Family |
Alpha-carbonic anhydrase family |
| Associated Diseases |
Hyperchlorhidrosis, isolated (HCHLH) |
| Tissue Specificity |
Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat gl |
