| Product Name |
Recombinant Human C9 Protein |
| Product Overview |
This recombinant human C9 protein includes amino acids 22-559aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P02748 |
| Recommended Name |
Complement component C9 |
| Gene Name |
C9 |
| Synonyms |
Complement component C9 precursor , Complement component 9 |
| Species |
Human |
| Predicted Molecular Mass |
63.4 kDa |
| Expression System |
E.coli |
| Expression Range |
22-559aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. |
| Subcellular Location |
Secreted. Target cell membrane; Multi-pass membrane protein. |
| Protein Family |
Complement C6/C7/C8/C9 family |
| Associated Diseases |
Complement component 9 deficiency (C9D); Macular degeneration, age-related, 15 (ARMD15) |
| Tissue Specificity |
Plasma (at protein level). |
