| Product Name |
Recombinant Human Complement Component 1, Q Subcomponent A (C1qA) Protein |
| Product Overview |
This recombinant human Complement Component 1, Q Subcomponent A (C1qA) protein includes amino acids 28-245aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P02745 |
| Recommended Name |
Complement C1q subcomponent subunit A |
| Gene Name |
C1QA |
| Synonyms |
Complement Component 1,q Subcomponent,Alpha Polypeptide |
| Species |
Human |
| Predicted Molecular Mass |
30 kDa |
| Expression System |
E.coli |
| Expression Range |
28-245aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| Subcellular Location |
Secreted. |
| Associated Diseases |
Complement component C1q deficiency (C1QD) |
