| Product Name |
Recombinant Human Breast Carcinoma Amplified Sequence 2 (BCAS2) Protein |
| Product Overview |
This recombinant human Breast Carcinoma Amplified Sequence 2 (BCAS2) protein includes amino acids 1-225aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O75934 |
| Recommended Name |
Pre-mRNA-splicing factor SPF27 |
| Gene Name |
BCAS2 |
| Synonyms |
Pre-mRNA-splicing factor SPF27, DAM1, Snt307, SPF27. |
| Species |
Human |
| Predicted Molecular Mass |
30.3 kDa |
| Expression System |
E.coli |
| Expression Range |
1-225aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Tags & Cell Markers |
| Target Function |
Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). |
| Subcellular Location |
Nucleus. Nucleus, nucleolus. |
| Protein Family |
SPF27 family |
| Tissue Specificity |
Ubiquitously expressed. |
