| Product Name |
Recombinant Human B7-1 (CD80) Protein |
| Product Overview |
This recombinant human B7-1 (CD80) protein includes amino acids 1-242aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P33681 |
| Recommended Name |
T-lymphocyte activation antigen CD80 |
| Gene Name |
CD80 |
| Synonyms |
B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;LAB7 |
| Species |
Human |
| Predicted Molecular Mass |
25.5 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
1-242aa |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.; (Microbial infection) Acts as a receptor for adenovirus subgroup B. |
| Subcellular Location |
Membrane; Single-pass type I membrane protein. |
| Tissue Specificity |
Expressed on activated B-cells, macrophages and dendritic cells. |
