| Product Name |
Recombinant Human Apolipoprotein A5 (APOA5) Protein |
| Product Overview |
This recombinant human Apolipoprotein A5 (APOA5) protein includes amino acids 167-335aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q6Q788 |
| Recommended Name |
Apolipoprotein A-V |
| Gene Name |
APOA5 |
| Synonyms |
Apolipoprotein A-V precursor, Apolipoprotein A-V, APOAV; RAP3 |
| Species |
Human |
| Predicted Molecular Mass |
20 kDa |
| Expression System |
E.coli |
| Expression Range |
167-335aa |
| Tag |
N-6His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin. |
| Subcellular Location |
Secreted. Early endosome. Late endosome. Golgi apparatus, trans-Golgi network. |
| Protein Family |
Apolipoprotein A1/A4/E family |
| Associated Diseases |
Hypertriglyceridemia, familial (FHTR); Hyperlipoproteinemia 5 (HLPP5) |
| Tissue Specificity |
Liver and plasma. |
