| Product Name |
Recombinant Human Anthrax Toxin Receptor 1 (ANTXR1) Protein |
| Product Overview |
This recombinant human Anthrax Toxin Receptor 1 (ANTXR1) protein includes amino acids 33-321aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q9H6X2 |
| Recommended Name |
Anthrax toxin receptor 1 |
| Gene Name |
ANTXR1 |
| Synonyms |
Anthrax Toxin Receptor 1; Tumor Endothelial Marker 8; ANTXR1; ATR; TEM8 |
| Species |
Human |
| Predicted Molecular Mass |
33.6 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
33-321aa |
| Tag |
C-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Tags & Cell Markers |
| Target Function |
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.; (Microbial infection) Acts as a receptor for protective antigen (PA) of B.anthracis. |
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. |
| Protein Family |
ATR family |
| Associated Diseases |
Hemangioma, capillary infantile (HCI); GAPO syndrome (GAPO) |
| Tissue Specificity |
Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. |
