| Product Name |
Recombinant Human AKR7A3 Protein |
| Product Overview |
This recombinant human AKR7A3 protein includes amino acids 1-331aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in 20mM Tris-HCl buffer (pH8.0) containing 0.1mM NaCl, 10% glycerolprior to lyophilization. |
| Target Uniprot Id |
O95154 |
| Recommended Name |
Aflatoxin B1 aldehyde reductase member 3 |
| Gene Name |
AKR7A3 |
| Synonyms |
Aldo-keto reductase family 7, member A 3; Aflatoxin B1 aldehyde reductase, member 3; AFB1 aldehyde reductase 2(AFAR2). |
| Species |
Human |
| Predicted Molecular Mass |
41.6 kDa (370aa) |
| Expression System |
E.coli |
| Expression Range |
1-331aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
20mM Tris-HCl buffer (pH8.0) containing 0.1mM NaCl, 10% glycerol |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
| Subcellular Location |
Cytoplasm. |
| Protein Family |
Aldo/keto reductase family, Aldo/keto reductase 2 subfamily |
| Tissue Specificity |
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium. |
