| Product Name |
Recombinant Human Adiponectin Receptor 1 (ADIPOR1) Protein |
| Product Overview |
This recombinant human Adiponectin Receptor 1 (ADIPOR1) protein includes amino acids 1-136aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
Q96A54 |
| Recommended Name |
Adiponectin receptor protein 1 |
| Gene Name |
ADIPOR1 |
| Synonyms |
ACDCR1; CGI45; PAQR1; TESBP1A; TESBP1-A; Progestin and AdipoQ Receptor Family Member I |
| Species |
Human |
| Predicted Molecular Mass |
46 kDa |
| Expression System |
E.coli |
| Expression Range |
1-136aa |
| Tag |
N-His-GST |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular |
| Target Function |
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. |
| Protein Family |
ADIPOR family |
| Tissue Specificity |
Widely expressed. Highly expressed in heart and skeletal muscle. Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine. |
