| Product Name |
Recombinant Human Alcohol Dehydrogenase Class 4 Mu/ADH7 Protein |
| Product Overview |
This recombinant human Alcohol Dehydrogenase Class 4 Mu/ADH7 protein includes amino acids 1-386aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P40394 |
| Recommended Name |
All-trans-retinol dehydrogenase [NAD(+)] ADH7 |
| Gene Name |
ADH7 |
| Synonyms |
Alcohol Dehydrogenase Class 4 Mu/Sigma Chain; Alcohol Dehydrogenase Class IV Mu/Sigma Chain; Gastric |
| Species |
Human |
| Predicted Molecular Mass |
42.5 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
1-386aa |
| Tag |
C-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Metabolism, Signal Transduction |
| Target Function |
Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation. |
| Subcellular Location |
Cytoplasm. |
| Protein Family |
Zinc-containing alcohol dehydrogenase family, Class-IV subfamily |
| Tissue Specificity |
Preferentially expressed in stomach. |
![SDS-PAGE analysis of Human ADH7 (All-Trans-Retinol Dehydrogenase [Nad(+)] Adh7) - Recombinant Protein, showing >85% purity under 15% SDS-PAGE (Reduced)](http://www.astorscientific.us/cdn/shop/files/1gsgf8u9t57n4klj.jpg?v=1755751760&width=1000)
![SDS-PAGE analysis of Human ADH7 (All-Trans-Retinol Dehydrogenase [Nad(+)] Adh7) - Recombinant Protein, showing >85% purity under 15% SDS-PAGE (Reduced)](http://www.astorscientific.us/cdn/shop/files/1gsgf8u9t57n4klj.jpg?v=1755751760&width=88)
![SDS-PAGE analysis of Human ADH7 (All-Trans-Retinol Dehydrogenase [Nad(+)] Adh7) - Recombinant Protein, showing >85% purity under 15% SDS-PAGE (Reduced)](http://www.astorscientific.us/cdn/shop/files/1gsgf8u9t57n4klj.jpg?v=1755751760&width=640)
