| Description |
Recombinant Human ABO Protein is expressed from HEK293 with hFc tag at the N-terminus.It contains Ala54-Pro354. |
| Purity |
> 95% as determined by Tris-Bis PAGE |
| Accession |
ADX99264.1 |
| Target Symbol |
ABO |
| Species |
Human |
| Expression System |
HEK293 |
| Tag |
N-hFc |
| Expression Range |
Ala54-Pro354 |
| Mol. Weight |
The protein has a predicted MW of 60.56 kDa. Due to glycosylation, the protein migrates to 62-70 kDa based on Tris-Bis PAGE result. |
| Form |
Liquid |
| Formulation |
Supplied as 0.22um filtered solution in 20mM Tris, 150mM NaCl, 500mM L- Arginine, 2mM DTT (pH 7.0). |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping |
Shipped with dry ice. |
| Gene Background |
Histo-blood group ABH (O) antigens are major alloantigens in humans. These antigens are widely distributed in human tissues and undergo changes in expression during cellular differentiation and malignant development. The ABH antigens have been characterized as terminal disaccharide determinants which represent secondary gene products. They are synthesized in a stepwise fashion from a precursor by the action of different glycosyltransferases. |
