| Product Name |
Recombinant Human 4-Aminobutyrate Aminotransferase (ABAT) Protein |
| Product Overview |
This recombinant human 4-Aminobutyrate Aminotransferase (ABAT) protein includes amino acids 249-500 of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitolprior to lyophilization. |
| Target Uniprot Id |
P80404 |
| Recommended Name |
4-aminobutyrate aminotransferase, mitochondrial |
| Gene Name |
ABAT |
| Synonyms |
GABAT; L-AIBAT; 4-Anobutyrate Tansaminase; (S)-3-amino-2-methylpropionate transaminase; Gamma-amino-N-butyrate transaminase |
| Species |
Human |
| Predicted Molecular Mass |
32kDa |
| Expression System |
E.coli |
| Expression Range |
249-500 |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Neuroscience |
| Target Function |
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. |
| Subcellular Location |
Mitochondrion matrix. |
| Protein Family |
Class-III pyridoxal-phosphate-dependent aminotransferase family |
| Associated Diseases |
GABA transaminase deficiency (GABATD) |
| Tissue Specificity |
Liver > pancreas > brain > kidney > heart > placenta. |
