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TribioScience | SKU: TBI1366-100MG

Propargylglycine (R,S), H2S synthase inhibitor (TBI1366)

Name: Propargylglycine (R,S), H2S synthase inhibitor (TBI1366)
Brand: TribioScience
SKU: TBI1366-100MG
Price: 68.4 USD
Availability: InStock

$68.40

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Product Description

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TribioScience

Propargylglycine (R,S), H2S synthase inhibitor (TBI1366)

From $68.40

Description

Product Details

Formal Name: 2-Amino-4-pentynoic acid

Molecular Formula: C₅H₇NO₂

Formula Weight: 113.12

CAS Number: 64165-64-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 10 mg/ml) or in Water (up to 10 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

H2S synthase inhibitor

Functions

Irreversible inhibitor of the hydrogen sulfide biosynthesis enzyme, cystathione-γ-lyase. It inhibits H2S production in rat liver preparations (IC50=55 μM) and inhibits the rise in plasma H2S in rats with hemorrhagic shock. It reduces inflammation in a rodent carrageenan-induced hindpaw edema model. Ameliorates gentamycin-induced nephrotoxicity.

Application Procedures

First dissolved in DMSO (up to 10 mg/ml) or in Water (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

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