PP1, Src family kinase inhibitor

Description

Product Details

Formal Name: 4-amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine

Molecular Formula: C₁₆H₁₉N₅

Formula Weight: 281.63

CAS Number: 172889-26-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Src family kinase inhibitor

Functions

Potent and selective inhibitor of Src family tyrosine kinases. IC50=5 nM (p65lck), IC50=6 nM(P59fynT), IC50=170 nM (p60src). Cell permeable.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.