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TribioScience | SKU: TBI4496-10MG

PNU-282987, Nicotinic acetylcholine receptor agonist; cognition enhancer (TBI4496)

Name: PNU-282987, Nicotinic acetylcholine receptor agonist; cognition enhancer (TBI4496)
Brand: TribioScience
SKU: TBI4496-10MG
Price: 72.0 USD
Availability: InStock

$72.00

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TribioScience

PNU-282987, Nicotinic acetylcholine receptor agonist; cognition enhancer (TBI4496)

From $72.00

Description

Product Details

Formal Name: N-(3R)-1-Azabicyclo[2.2.2}oct-3-yl-4-chlorobenzamide

Molecular Formula: C₁₄H₁₇ClN₂O

Formula Weight: 264.75

CAS Number: 123464-89-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Nicotinic acetylcholine receptor agonist; cognition enhancer

Functions

PNU 282987 is a selective α7 nicotinic acetylcholine receptor (nAChR) agonist (Ki = 26 nM). The α7 nAChR is a potential therapeutic target of cognitive deficits in diseases such as Alzheimers, Parkinsons, schizophrenia, and attention deficit disorders – agonism of this receptor with PNU 282987 has shown potential to ameliorate these deficits.