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TribioScience  |  SKU: TBI2864-10MG

Plerixafor, CXCR4 antagonist (TBI2864)

$117.00
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TribioScience

Plerixafor, CXCR4 antagonist (TBI2864)

From $117.00

Description

Product Details

Formal Name: 1,1’-[1,4-Phenylenebis-(methylene)]-bis(1,4,8,11-tetraazacyclotetradecane), octahydrochloride

Alternate Names: AMD3100

Molecular Formula: C28H54N8·8HCl

Formula Weight: 794.5

CAS Number: 110078-46-1

Purity: >98%

Formulation: Powder

Solubility: Soluble in Water (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

CXCR4 antagonist

Functions

Plerixafor is a highly selective CXCR4 antagonist (IC50 = 20-130 nM). Originally investigated as an HIV replication inhibitor. Plerixafor has been investigated for the treatment autoimmune diseases and various cancers. Clinically useful for the mobilization of hematopoietic stem cells in the treatment of blood cancers.

Application Procedures

First dissolved in Water (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 2 months.

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  • 10 MG
  • 50 MG
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