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TribioScience | SKU: TBI1180-5MG

Pifithrin mu, Hsp70 inhibitor (TBI1180)

Name: Pifithrin mu, Hsp70 inhibitor (TBI1180)
Brand: TribioScience
SKU: TBI1180-5MG
Price: 81.0 USD
Availability: InStock

$81.00

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Product Description

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TribioScience

Pifithrin mu, Hsp70 inhibitor (TBI1180)

From $81.00

Description

Product Details

Formal Name: 2-Phenylethynesulfonamide

Alternate Names: PES; NSC-303580

Molecular Formula: C₈H₇NO₂S

Formula Weight: 181.21

CAS Number: 64984-31-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Hsp70 inhibitor

Functions

Selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. Inhibits p53 binding to antiapoptotic proteins Bcl-xL and Bcl-2. Recues primary mouse thymocytes from P53-mediated apoptosis induced by radiation. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

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