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TribioScience  |  SKU: TBI2767-10MG

Ozagrel HCl, Thromboxane synthase inhibitor (TBI2767)

$101.00
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TribioScience

Ozagrel HCl, Thromboxane synthase inhibitor (TBI2767)

From $101.00

Description

Product Details

Formal Name: (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride

Alternate Names: OKY-046

Molecular Formula: C13H12N2O2 HCl

Formula Weight: 264.71

CAS Number: 78712-43-3

Purity: >98%

Formulation: powder

Solubility: Soluble in Water (up to 25 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Thromboxane synthase inhibitor

Functions

Potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM). Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2 isomerase (IC50 > 1 mM). Inhibits platelet aggregation in vitro and arachidonate-induced arterial contraction in vivo. Protects against arachidonate-induced sudden death in the rabbit. Alleviates liver injury induced by acetaminophen overdose in mice.

Application Procedures

First dissolved in Water (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in Water may be stored at -20°C for up to 1 month.

Option

  • 10 MG
  • 50 MG
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