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TribioScience | SKU: TBI1107-20MG

ONO-RS-082, Phospholipase A2 inhibitor (TBI1107)

Name: ONO-RS-082, Phospholipase A2 inhibitor (TBI1107)
Brand: TribioScience
SKU: TBI1107-20MG
Price: 99.0 USD
Availability: InStock

$99.00

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Product Description

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TribioScience

ONO-RS-082, Phospholipase A2 inhibitor (TBI1107)

From $99.00

Description

Product Details

Formal Name: 2-(4-Pentylcinnamoyl)amino-4-chlorobenzoic acid

Alternate Names: PACA

Molecular Formula: C₂₁H₂₂ClNO₃

Formula Weight: 371.86

CAS Number: 99754-06-0

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Phospholipase A2 inhibitor

Functions

Reversible inhibitor of Ca²⁺-independent phospholipase A₂ (PLA₂), IC50=7 μM for guinea pig lung PLA2. Inhibits epinephrine-induced thromboxane production in platelets. Inhibition of PLA₂ by ONO-RS-032 disrupts endosome tubule formation and maintenance of the Golgi complex. Prevents Xenopus oocyte maturation at stage V.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.

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