Oligomycin complex, Mitochondrial ATPase inhibitor (TBI2092)

Description

Product Details

Formal Name: From Streptomyces sp., mixture of Oligomycin A, B, and C

Molecular Formula: C₄₅H₇₄O₁₁ (for Oligomycin A)

Formula Weight: 791.10

CAS Number: 1404-19-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 300 mg/ml) or in Ethanol (up to 200 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Mitochondrial ATPase inhibitor

Functions

Inhibits mitochondrial F1F0 ATP synthase. A useful tool for decreasing cellular ATP levels. Induces autophagy. Stimulates lysosome acidification. Protects against ischemic kidney in male rats.

Application Procedures

First dissolved in DMSO (up to 300 mg/ml) or in Ethanol (up to 200 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.