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TribioScience | SKU: TBI1350-5MG

Nutlin-3, p53/mdm2 inhibitor (TBI1350)

Name: Nutlin-3, p53/mdm2 inhibitor (TBI1350)
Brand: TribioScience
SKU: TBI1350-5MG
Price: 180.0 USD
Availability: InStock

$180.00

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Product Description

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TribioScience

Nutlin-3, p53/mdm2 inhibitor (TBI1350)

From $180.00

Description

Product Details

Formal Name: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one

Molecular Formula: C₃₀H₃₀Cl₂N₄O₄

Formula Weight: 581.51

CAS Number: 548472-68-0

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

p53/mdm2 inhibitor

Functions

MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells.

Application Procedures

First dissolved in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

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