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TribioScience | SKU: TBI1334-10MG

NSC-66811 p53/mdm2 inhibitor (TBI1334)

Name: NSC-66811 p53/mdm2 inhibitor (TBI1334)
Brand: TribioScience
SKU: TBI1334-10MG
Price: 180.0 USD
Availability: InStock

$180.00

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TribioScience

NSC-66811 p53/mdm2 inhibitor (TBI1334)

From $180.00

Description

Product Details

Formal Name: 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol

Molecular Formula: C₂₃H₂₀N₂O

Formula Weight: 340.43

CAS Number: 6964-62-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

p53/mdm2 inhibitor

Functions

A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

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50 MG

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NSC-66811 p53/mdm2 inhibitor (TBI1334)

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Product Description