Welcome to Astor Scientific

New collections added! Learn more

TribioScience  |  SKU: TBI1352-5MG

NSC-663284, Cdc25 Phosphatase inhibitor (TBI1352)

$162.00
Shipping calculated at checkout.


Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Payment & Security

Payment methods

  • American Express
  • Apple Pay
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • PayPal
  • Shop Pay
  • Venmo
  • Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.


Product Description


Product Reviews

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
TribioScience

NSC-663284, Cdc25 Phosphatase inhibitor (TBI1352)

From $162.00

Description

Product Details

Formal Name: 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione

Molecular Formula: C15H16ClN3O3

Formula Weight: 321.77

CAS Number: 383907-43-5

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 55 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Cdc25 Phosphatase inhibitor

Functions

Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation. Inhibits the growth of a variety of human tumor cell lines. Acts via irreversible oxidation of the catalytic cysteine of CDC25.

Application Procedures

First dissolved in DMSO (up to 15 mg/ml), or in Ethanol (up to 55 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

Option

  • 5 MG
  • 25 MG
View product
close
close
I have a question
sparkles
close
product
Hello! I am very interested in this product.
gift
Special Deal!
sparkles