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TribioScience  |  SKU: TBI1385-10MG

NSC-632839, DUB inhibitor (TBI1385)

$117.00
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TribioScience

NSC-632839, DUB inhibitor (TBI1385)

From $117.00

Description

Product Details

Formal Name: 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride

Alternate Names: F6

Molecular Formula: C21H21NO · HCl

Formula Weight: 339.86

CAS Number: 157654-67-6

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 8 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

DUB inhibitor

Functions

A pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway. Cell permeable..

Application Procedures

First dissolved in DMSO (up to 8 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.

Option

  • 10 MG
  • 50 MG
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