Nonactin, Monovalent cation ionophore (K+ and NH4+) (TBI2090)

Description

Product Details

Formal Name: Isolated from Streptomyces griseus

Alternate Names: Polynactin; Werramycin A

Molecular Formula: C₄₀H₆₄O₁₂

Formula Weight: 736.95

CAS Number: 6833-84-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Monovalent cation ionophore (K+ and NH4+)

Functions

Monovalent cation ionophore with high selectivity for NH₄⁺ and K⁺. Upregulates levels of mitochondrial stress proteins HSP58 and GRP75. Abolishes mitochondrial membrane potential.

Application Procedures

First dissolved in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.