Nalmefene HCl, Opioid receptor antagonist (TBI1049)

Description

Product Details

Formal Name: 5(α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylene-morphinan-3,14-diol hydrochloride

Alternate Names: Nalmetrene

Molecular Formula: C₂₁H₂₅NO₃ · HCl

Formula Weight: 375.82

CAS Number: 58895-64-0

Purity: >98%

Formulation: powder

Solubility: Soluble in Water (up to 25 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Opioid receptor antagonist

Functions

Opioid antagonist. Very similar activity profile to naloxone however displays slower onset and longer duration of action. Antagonizes the effects of salvinorin (κ-agonist) as well as herkinorin (μ-agonist). Has been used as a therapeutic for treatment of alcohol dependence.

Application Procedures

First dissolved in Water (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 1 month.